Fig. 8From: D-allose Inhibits TLR4/PI3K/AKT Signaling to Attenuate Neuroinflammation and Neuronal Apoptosis by Inhibiting Gal-3 Following Ischemic StrokePotential mechanisms by which D-allose exerts neuroprotective effects against I/R-induced brain injury in mice and HT-22 cells. D-allose protects the brain from ischemia reperfusion-induced apoptosis and inflammation by suppressing Gal-3 expression and transcriptional processes that inhibit TLR4 and activate PI3K/AKT phosphorylationBack to article page