Fig. 2

Effects of D-allose on cytotoxicity and apoptosis induced by OGD/R in HT-22 cells. A HT-22 cells were subjected to OGD damage for different times, and cell viability was determined by CCK-8 assays. B HT-22 cells were subjected to OGD/R injury, and LDH levels were measured. C Cell viability was determined by CCK-8 assays after the administration of D-allose. D Detection of LDH levels after D-allose treatment. E Effects of D-allose on the expression levels of Bax, Bcl-2, Caspase 3, and Caspase 1 in HT-22 cells subjected to OGD/R. F Effects of D-allose on HT-22 cell apoptosis induced by OGD/R, as determined by TUNEL staining.  The effects of D-allose on the levels of TNF-α (G), IL-1β (H) and IL-6 (I) were measured by ELISA kits.  **P<0.01 compared with the Con group; ^##P<0.01 compared with the OGD/R group. The Data were analyzed using one-way ANOVA, and Dunnett’s test was used for post hoc analysis. The data were from three independent experiments