Fig. 4
Effect of R1-MVs on the activities of antioxidant enzymes (SOD and CAT), level of GSH, and MDA content in H2O2-treated HaCaT cells. Cells were pretreated with different concentrations of R1-MVs (5, 10, and 30 μg/mL) for 12 h, followed by treatment with 0.3 mM H2O2 for 12 h. A Malondialdehyde (MDA) content, (B) oxidized glutathione (GSSG) content, (C) glutathione (GSH) content, (D) GSH/GSSG ratio, (E) superoxide dismutase (SOD) activity, and (F) catalase (CAT) activity assessed in HaCaT cells. ###p < 0.001 vs. control group; *p < 0.05, **p < 0.01, or ***p < 0.001 vs. H2O2-treated group. The data show the mean ± SD (n = 4 samples) of three representative experiments