Fig. 4

Unsupervised clustering of deep learning features in TCGA-UVM cohort. A Comprehensive heatmap with unsupervised clustering showed distinctive characteristics of deep learning features and clinical characteristics. B Kaplan–Meier curve of survival probability between Cluster1 and Cluster2 subtype. C Boxplot of the 14 deep learning features between alive and dead status. D Heatmap of 50 cancer Hallmark pathways between Cluster1 and Cluster2 subtypes. E Comprehensive OncoPrint plots of mutated characteristics in Cluster1 and Cluster2 subtypes. F Boxplot of TMB between Cluster1 and Cluster2 subtypes. G Boxplot of MSI between Cluster1 and Cluster2 subtypes. H The distributions of mutational signatures in Cluster1 and Cluster2 subtypes. I Forest plots of the top mutated genes between Cluster1 and Cluster2 subtypes