Fig. 6

Clinical diagnostic value of MMP-9 and MMP-2 for FC rupture. A The protein concentration of MMP-9 in the ruptured FC tissues was found to be significantly higher than that in intact FC tissues (P = 0.0156). B The protein concentration of MMP-2 in ruptured FC tissues was observed significantly higher than that in intact FC tissues (P = 0.0267). C The protein concentration of MMP-9 in serum was significantly higher in ruptured FC patients than in intact FC patients (p < 0.0001). D The protein concentration of MMP-2 in serum was significantly higher in ruptured FC patients than in intact FC patients (p < 0.0001). E ROC curve to determine the optimal cutoff value for tissue MMP-9. The optimal cutoff value for MMP-9 was 27,007.56 ng/g (sensitivity 63.2%; specificity 89.5%). F ROC curve to determine the optimal cutoff value for tissue MMP-2. The optimal cutoff value for MMP-2 was 1622.70 ng/g (sensitivity 89.5%; specificity 57.9%). G ROC curve to determine the optimal cutoff value for serum MMP-9. The optimal cutoff value for MMP-9 was 630.8191 ng/ml (sensitivity 100%; specificity 100%). H ROC curve to determine the optimal cutoff value for serum MMP-2. The optimal cutoff value for MMP-2 was 132.9021 ng/ml (sensitivity 100%; specificity 100%). RFC indicates the ruptured fibrous capsule; IFC indicates the intact fibrous capsule