Fig. 6

PPP2CA mediated the tumor suppressive functions of YTHDF2 in GC. A The knockdown efficiencies of PPP2CA in GC cells transiently transfected with siRNAs against PPP2CA were tested by western blot analysis. B-D Cell viabilities and migratory abilities were determined using CCK8 assays (B), colony formation assays (C) and transwell assays (D) in HGC27 and MGC803 cells with stable YTHDF2 overexpression and transfection with PPP2CA siRNA