Fig. 5

PPP2CA was modulated by YTHDF2 in gastric cancer cells. A Data were analyzed by informatics methods from Co-expedia database to investigate co-expression genes of YTHDF2 in stomach cancer. B The correlation between YTHDF2 and PPP2CA mRNA expression level was calculated applying GEPIA (R = 0.59). C. The expression correlation between YTHDF2 and PPP2CA in 32 pairs of GC samples analyzed from qRT-PCR data. D, E The mRNA levels of YTHDF2 and PPP2CA in YTHDF2 stably overexpressed or down-regulated GC cells. F, G The protein levels of YTHDF2 and PPP2CA in YTHDF2 stably overexpressed or down-regulated GC cells. H The mRNA levels of YTHDF2, PPP2CA and FOXC2 in gastric cancer cells where empty vector, YTHDF2-WT and YTHDF2-MUT plasmids were transiently transfected, respectively