Fig. 4
YTHDF2 overexpression attenuated tumorigenicity and metastasis of gastric cancer cell in vivo. A YTHDF2 Knockdown increased the carcinogenesis of SGC7901 and BGC823 stable cell lines in nude mice by comparing the sizes and weights of xenografts. B Overexpression of YTHDF2 decreased the tumorigenicity of MGC803 stable cell line in nude mice. C Knockdown of YTHDF2 promoted pulmonary metastasis of SGC7901 cells. Representative lung tissue images (left), H&E staining pictures of the whole tissues (middle) and statistical data of quantity of metastatic micronodules per lung section(right)