Fig. 1

YTHDF2 was aberrantly decreased and negatively related to poor prognosis in GC. A Characterization of YTHDF2 protein expression in 90 pairs of gastric tissues with negative (-), weak ( +), moderate (+ +) and strong (+ + +) levels by IHC staining and representative pictures were shown. Magnification: 200 × . B The results of IHC staining were shown in the composite column diagram. Low expression: (-) and ( +); high expression (+ +) and (+ + +). C Kaplan–Meier plot of different GC patients’ groups divided by YTHDF2 expression level. Survival analysis was evaluated by log-rank test. D qRT-PCR results of YTHDF2 mRNA expression in 32 pairs of GC samples. Data are presented as fold changes of YTHDF2 mRNA expression in gastric tissue (C: gastric cancer tissues; N, gastric non-cancer tissues). E Percentage of YTHDF2 expression level change in additional 32 pairs of stomach cancer clinical samples