Fig. 3

Circ_0003570 acts as a sponge of miR-182-5p to regulate STARD13. A Bioinformatics analysis showed the binding site between circ_0003570 and miR-182-5p. B A dual luciferase reporter assay was applied to verify the targeted binding effect between circ_0003570 and miR-182-5p. **P < 0.01. C Bioinformatics analysis showed the binding site between miR-182-5p and STARD13 3′‐UTR. D A dual luciferase reporter assay was applied to verify the targeted binding effect between circ_0003570 and miR-182-5p. **P < 0.01. E, F qRT-PCR analysis of miR-182-5p expression following transfected HCC cells with siRNA or overexpressed lentiviral vector of circ_0003570. *P < 0.05; **P < 0.01. G The STARD13 mRNA levels after miR-182-5p overexpression or downregulation were deceted by qRT-PCR. *P < 0.05. H The STARD13 protein levels after miR-182-5p overexpression or downregulation were deceted by western blot. Student’s t-test was performed to compare the difference between two groups