Fig. 5
From: AVL9 promotes colorectal carcinoma cell migration via regulating EGFR expression
AVL9 promoted CRC cell migration via regulating EGFR expression. A Rescue experiment showed that decreased EGFR expression could partially suppressed the increased migration in DLD1-Lv6-AVL9 compared to DLD1-Lv6-NC cell. Cells were treated or not with concentrations of cetuximab (1μM). B GSEA showed that ERBB signaling pathway was upregulated in AVL9 high expression group. The CRC patients were categorized into high expression group and low expression group by mean expression of AVL9. *P<0.05, **P<0.01