Fig. 3
From: A rat model for retinitis pigmentosa with rapid retinal degeneration enables drug evaluation in vivo
mRNA expression analysis. mRNA expression levels of various genes in retinas of the wildtype and P347L rats at the age of 10 days were analyzed and compared by real-time PCR. mRNA expression levels of ER stress markers CHOP and Bip were significantly higher in P347L rats than in wild-type rats (a, b). mRNA expression levels of autophagy related molecules LC3 and Atg5 were significantly increased in P347L rats (c, d). Unpaired t test: *p < 0.05; ***p < 0.001. n = 3