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Table 2 List of circRNAs related to Cardiovascular Diseases

From: Deep Insights in Circular RNAs: from biogenesis to therapeutics

Disease TypeCircRNATargetsEffect on DiseasesRef.
Heart failure and pathological hypertrophyHRCRmmiR-223, ARCSuppressionWang et al., 2016
Myocardial InfarctionCdr1as (ciRS-7)miR-7, SP1, PARPInductionGeng et al., 2016
Cardiac senescenceCirc-Foxo3ID1,E2F1,FAK,HIF1aSuppressionDu et al., 2017
AtherosclerosiscANRILINK4/ARF locusRegulationSong et al., 2017
hsa_circ_0003575miR-199-3p, miR-9-5p, miR-377-3p and miR-141-3pRegulates oxLDL induced vascular endothelial cells proliferation and angiogenesisLi et al., 2017
hsa_circ_0010729miR-186/HIF-1α axisRegulates vascular endothelial cells proliferation and apoptosisDang et al., 2017
CardiomyopathyCirc-Amotl1AKT1RegulationZeng et al., 2017
Myocardial FibrosisCircRNA_010567miR-141, TGF- β1, Col I, α-SMA and Col IIIPromotes FibrosisZhou et al., 2017
Coronary artery diseasehsa_circ_0124644BiomarkerZhao et al., 2017
hsa -circRNA11783–2No functional role elucidated