Table 1 Telomere-associated variables
Variable type | Variable name | Description |
|---|---|---|
Descriptive statistics | Total Nuclei | Total number of nuclei in the sample. |
StDevPromedioI2 | Standard deviation of the I2 median of the wells in a sample | |
CoVPromedioI2 | Variation Coefficient of the I2 median of the wells in a sample | |
LengthI2Normalized | TL corresponding to the normalization of the median of intensities | |
Length20Percentil | TL corresponding to the normalization of the 20th percentile of the intensities of a sample | |
TamPromedio | Average nucleus size per sample | |
MedianI2 | Median of intensities per sample | |
MedianI2Normalized | Normalization of the median of intensities per sample | |
LengthAVG_I2 | Average telomeric length of the telomeres in a sample | |
SDMedianLength | Standard deviation of the median telomere lengths of the wells of a sample. | |
CVMedianLength | Variation coefficient of the median TL of the wells of a sample | |
Telomere Length Percentiles | Percentil N | TL corresponding to the Nth percentile of a sample. Percentiles 1 and 100 are not included (up to 98 values) |
Percentages of telomeric length values (ShortTel) | ShortTel N | Percentage of telomeres of a sample with a TL under the threshold N (80 values; i.e.: < 3 Kbp) |
Percentages of cells with specific telomere values (ShortCell) | ShortCell N | Percentage of cells of a sample whose telomeres average a length under the threshold N (40 values) |
Dispersion | MAD-I2 | Median Absolute Deviation of the intensities of a sample |
P1–99-Kpbs | Difference between the 99th percentile of the TLs of a sample and the 1st percentile of the telomere lengths of that sample. | |
P75–25-Kpbs | Interquartile of the TLs of a sample. |