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Table 1 Telomere-associated variables

From: Analytical Validation of Telomere Analysis Technology® for the High-Throughput Analysis of Multiple Telomere-Associated Variables

Variable typeVariable nameDescription
Descriptive statisticsTotal NucleiTotal number of nuclei in the sample.
StDevPromedioI2Standard deviation of the I2 median of the wells in a sample
CoVPromedioI2Variation Coefficient of the I2 median of the wells in a sample
LengthI2NormalizedTL corresponding to the normalization of the median of intensities
Length20PercentilTL corresponding to the normalization of the 20th percentile of the intensities of a sample
TamPromedioAverage nucleus size per sample
MedianI2Median of intensities per sample
MedianI2NormalizedNormalization of the median of intensities per sample
LengthAVG_I2Average telomeric length of the telomeres in a sample
SDMedianLengthStandard deviation of the median telomere lengths of the wells of a sample.
CVMedianLengthVariation coefficient of the median TL of the wells of a sample
Telomere Length PercentilesPercentil NTL corresponding to the Nth percentile of a sample. Percentiles 1 and 100 are not included (up to 98 values)
Percentages of telomeric length values (ShortTel)ShortTel NPercentage of telomeres of a sample with a TL under the threshold N (80 values; i.e.: < 3 Kbp)
Percentages of cells with specific telomere values (ShortCell)ShortCell NPercentage of cells of a sample whose telomeres average a length under the threshold N (40 values)
DispersionMAD-I2Median Absolute Deviation of the intensities of a sample
P1–99-KpbsDifference between the 99th percentile of the TLs of a sample and the 1st percentile of the telomere lengths of that sample.
P75–25-KpbsInterquartile of the TLs of a sample.
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