Table 1 Comparison with other methods
From: Cell-Wide Survey of Amide-Bonded Lysine Modifications by Using Deacetylase CobB
Advantage | Disadvantage | |
|---|---|---|
Our method | 1. Multiple modifications identification 2. Known the demodification enzyme | 1. Only amide-bond lysine modifications 2. Higher false positive ratio 3. More expertise needed |
Biochemical Journal, 1963 | 1. Lower false positive ratio 2. Less expertise needed | 1. Only amide-bond lysine modifications 2. One modification identification 3. Unkown the demodification enzyme |
Molecular & Cellular Proteomics, 2007 | 1. Lower false positive ratio 2. Less expertise needed | 1. Only amide-bond lysinemodifications 2. One modification identification 3. Unkown the demodification enzyme |