Fig. 4

Morphological analysis of the 16dpc gonads of control (C), culture-control (CC) and 5-Aza-CdR-treated gonads. In the C (a) and CC (b) gonads the seminiferous cords can be clearly distinguished. In the gonads treated with 1 μM fo 5-Aza-CdR (AzaC1; c) it still possible to note the cordonal organization, which is less evident in the gonads treated with 3 μM of 5-Aza-CdR (AzaC3; d). The gonads treated with 5 μM of 5-Aza-CdR (AzaC5; e) very few PGC are observed (arrow) and most of the gonad consisted of somatic cells (*)