Fig. 7

Andrographolide enhanced NK cell tumoricidal activity. NSCLC cells or NK cells were pretreated for 24 h with andrographolide, 5 and 10 μM concentrations, respectively. Later NK cells cytotoxicity was evaluated by calcein release assay with a 5:1 ratio of effectors to target cells. Panel a, A549 cells; Panel b, H1299 cells. The data shown here are representative of three independent experiments. Data are expressed as means ± S.E.M. *, P<0.05; **, P<0.01; ***, P<0.001