Table 1 Comparison of in silico digestions (double vs. single digestion)
From: Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples
Covered by MspI single digestion | Covered by MspI and TaqαI double digestion | Percentage of increase (double vs. single digestion) | |
|---|---|---|---|
CpGs in CGI regions | 1,098,462 | 1,180,058 | 7.4% |
CpGs in non-CGI regions | 1,919,174 | 2,720,858 | 41.8% |
CGIs* | 20,227 | 21,511 | 6.3% |
Promoters* (−1000 to +500 bp) | 24,520 | 27,633 | 12.7% |