Figure 2
From: Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples
Coverage of CpGs and genomic regions by RRBS. (A) An example for number of CpG sites with different minimum sequencing depths; (B) Distribution of CpGs in CGIs/CGSs/Others, using a sequencing depth ≥ 10 as the cutoff; (C) Distribution of CpGs in Promoter/TTR/Intragenic/Intergenic regions; (D) Distribution of genomic regions in CGIs/CGSs/others. (E) Distribution of genomic regions in promoter/TTR/Intragenic/Intergenic regions. A genomic region was considered covered if at least three CpGs within the region were sequenced at a depth ≥ 10.