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  1. YTHDF2 is one of important readers of N6-methyladenosine (m6A) modification on RNA. Growing evidence implicates that YTHDF2 takes an indispensable part in the regulation of tumorigenesis and metastasis in differe...

    Authors: Ying Zhou, Kailing Fan, Ning Dou, Li Li, Jialin Wang, Jingde Chen, Yandong Li and Yong Gao
    Citation: Biological Procedures Online 2023 25:6
  2. Lung cancer is the most common cause of cancer-related death globally. There are several reasons for this high mortality rate, including metastasis to multiple organs, especially the brain. Exosomes play a piv...

    Authors: Lingyun Ye, Yinfei Wu, Juan Zhou, Mengqing Xie, Zhemin Zhang and Chunxia Su
    Citation: Biological Procedures Online 2023 25:5
  3. Intraneuronal tau aggregation is the major pathological hallmark of neurodegenerative tauopathies. It is now generally acknowledged that tau aggregation also affects astrocytes in a cell non-autonomous manner....

    Authors: Kevin L. Batenburg, Claudia Sestito, Paulien Cornelissen-Steijger, Jan R. T. van Weering, Leo S. Price, Vivi M. Heine and Wiep Scheper
    Citation: Biological Procedures Online 2023 25:4
  4. Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into ce...

    Authors: Morvarid Ebadi, Amirfarhang Miresmaeili, Sarah Rajabi, Shahrokh Shojaei and Sareh Farhadi
    Citation: Biological Procedures Online 2023 25:2

    The Correction to this article has been published in Biological Procedures Online 2023 25:14

  5. P2RX7 is a purinergic receptor with pleiotropic activities that is activated by high levels of extracellular ATP that are found in inflamed tissues. P2RX7 has immunomodulatory and anti-tumor proprieties and is...

    Authors: Serena Janho dit Hreich, Thierry Juhel, Paul Hofman and Valérie Vouret-Craviari
    Citation: Biological Procedures Online 2023 25:1
  6. Sjogren’s syndrome (SS) is an autoimmune disorder characterized by the destruction of exocrine glands, resulting in dry mouth and eyes. Currently, there is no effective treatment for SS, and the mechanisms ass...

    Authors: Bo Chen, Jiannan Zhou, Tianjiao Mao, Tingting Cao, Shilin Hu, Wenqi Zhang, Xueyang Li, Xiuni Qin, Xintong Liu, Nobumoto Watanabe and Jiang Li
    Citation: Biological Procedures Online 2022 24:26
  7. Desmoid tumor (DT), also known as desmoid-type fibromatosis (DTF) or aggressive fibromatosis (AF) is a rare mesenchymal tumor affecting both children and adults. It is non-metastasis but infiltrative, growing ...

    Authors: Bo Ning, Peng Huang, Lining Zhu, Zhijie Ma, Xiaoli Chen, Haojun Xu, Ruixue Ma, Chengyun Yao, Pengfei Zheng, Tian Xia and Hongping Xia
    Citation: Biological Procedures Online 2022 24:25
  8. Cellular senescence is a tumor suppressive response in which the cell cycle is in a state of permanent arrest and can inhibit tumor cell proliferation. In recent years, induction of cellular senescence has bee...

    Authors: Liang Sun, Zitao Liu, Ke Ning, Zhipeng Wu, Zhendong Chen, Zhengyi Wu and Xiangbao Yin
    Citation: Biological Procedures Online 2022 24:24
  9. The chloroplast is a semi-autonomous organelle having its own genome and corresponding proteome. Although chloroplast genomes have been reported, no reports exist on their corresponding proteomes. Therefore, a...

    Authors: Tapan Kumar Mohanta, Yugal Kishore Mohanta and Ahmed Al-Harrasi
    Citation: Biological Procedures Online 2022 24:23
  10. Hepatocellular carcinoma (HCC) belongs to a representative lethality gastrointestinal malignancy, and comprehensive management of HCC remains intractable at present on account of its invasive biological featur...

    Authors: Xiangyu Li, Kai Zhao, Yun Lu, Jianming Wang and Wei Yao
    Citation: Biological Procedures Online 2022 24:22
  11. A variety of studies have connected circadian rhythm to the initiation and progression of hepatocellular carcinoma (HCC). The purpose of this study was to figure out about the circadian genes' profile characte...

    Authors: Mengqi Zhu, Jianping Zhang, Saiyan Bian, Xue Zhang, Yiping Shen, Zhiyu Ni, Shiyu Xu, Chun Cheng and Wenjie Zheng
    Citation: Biological Procedures Online 2022 24:21
  12. The emergence of antibiotic-resistant pathogens has threatened not only our ability to deal with common infectious diseases but also the management of life-threatening complications. Antimicrobial resistance (...

    Authors: Bashar Haruna Gulumbe, Usman Abubakar Haruna, Joseph Almazan, Ibrahim Haruna Ibrahim, Abdullahi Adamu Faggo and Abbas Yusuf Bazata
    Citation: Biological Procedures Online 2022 24:19
  13. Advances in next-generation sequencing technologies have accelerated the momentum of metagenomic studies, which is increasing yearly. The metagenomics field is one of the versatile applications in microbiology...

    Authors: Gauri S. Navgire, Neha Goel, Gifty Sawhney, Mohit Sharma, Prashant Kaushik, Yugal Kishore Mohanta, Tapan Kumar Mohanta and Ahmed Al-Harrasi
    Citation: Biological Procedures Online 2022 24:18

    The Correction to this article has been published in Biological Procedures Online 2024 26:8

  14. Phenotyping sputum-resident leukocytes and evaluating their functional status are essential analyses for exploring the cellular basis of pathological processes in the lungs, and flow cytometry is widely recogn...

    Authors: Giulia Santopolo, Antonio Clemente, Estrella Rojo-Molinero, Sara Fernández, María Concepción Álvarez, Antonio Oliver and Roberto de la Rica
    Citation: Biological Procedures Online 2022 24:17
  15. Micro RNA of Marsupenaeus japonicas has been known to promote apoptosis of tumor cells. However, the detailed mechanisms are not well understood.

    Authors: Hyueyun Kim, Ji Ha Choi, Chang Mo Moon, Jihee Lee Kang, Minna Woo and Minsuk Kim
    Citation: Biological Procedures Online 2022 24:16
  16. Angiotensin-converting enzyme 2 (ACE2) is known as a tumor suppressor and lowly expressed in most cancers. The expression pattern and role of ACE2 in breast cancer (BC) have not been deeply elucidated.

    Authors: Jie Mei, Yun Cai, Rui Xu, Xinqian Yu, Xu Han, Miaomiao Weng, Lingyan Chen, Tao Ma, Tianshu Gao, Fei Gao, Tiansong Xia, Yichao Zhu and Yan Zhang
    Citation: Biological Procedures Online 2022 24:15
  17. Emerging evidence have revealed that circRNAs exert important biological effects in the development and progression of various diseases, including cancer. Our study aimed to elaborated the biological effects o...

    Authors: Xu Zhang, Wenwen Chen, Dan Guo, Yarui Li, Yan Zhao, Mudan Ren, Guifang Lu, Xinlan Lu and Shuixiang He
    Citation: Biological Procedures Online 2022 24:14
  18. Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide. Single-cell transcriptome sequencing (scRNA-seq) can provide accurate gene expression data for individual cells. In this ...

    Authors: Ziyang Di, Sicheng Zhou, Gaoran Xu, Lian Ren, Chengxin Li, Zheyu Ding, Kaixin Huang, Leilei Liang and Yihang Yuan
    Citation: Biological Procedures Online 2022 24:13
  19. Bladder cancer (BCa) is a fatal form of cancer worldwide associated with a poor prognosis. Identifying novel drivers of growth and metastasis hold therapeutic potential for the disease. Transport homeostasis b...

    Authors: Xiangui Meng, Weiquan Li, Hongwei Yuan, Wei Dong, Wen Xiao and Xiaoping Zhang
    Citation: Biological Procedures Online 2022 24:12
  20. Liver inflammation is a multistep process that is linked with cell membrane fatty acids composition. The effectiveness of eicosapentaenoic acid (EPA) undergoes an irreversible change during processing due to t...

    Authors: Jihan Hussein, Mona A. El-Bana, Zakaria El-kHayat, Mehrez E. El-Naggar, Abdel Razik Farrag and Dalia Medhat
    Citation: Biological Procedures Online 2022 24:11
  21. The effects of Otubain-2 (OTUB2) on the proliferation, invasion, and migration of esophageal squamous cell carcinoma (ESCC) were investigated by interfering with OTUB2 expression.

    Authors: Li Liu, Hu Cheng, Min Ji, Liping Su, Ziyang Lu, Xiayun Hu, Yaling Guan, Jinling Xiao, Lijuan Ma, Wei Zhang and Hongwei Pu
    Citation: Biological Procedures Online 2022 24:10
  22. Long non-coding RNAs (lncRNA) have been implicated in a hand of studies that supported an involvement and co-operation in Uterine Corpus Endometrial Carcinoma (UCEC). Enhancer RNAs (eRNA), a functional subtype...

    Authors: Jinhui Liu, Jian Yin, Yuanyuan Wang, Lixin Cai, Rui Geng, Mulong Du, Zihang Zhong, Senmiao Ni, Xiaohao Huang, Hao Yu and Jianling Bai
    Citation: Biological Procedures Online 2022 24:9
  23. The growing detection of long noncoding RNAs (lncRNAs) required the application of functional approaches in order to provide absolutely precise, conducive, and reliable processed information along with effecti...

    Authors: Narjes Azadbakht, Abbas Doosti and Mohammad-Saeid Jami
    Citation: Biological Procedures Online 2022 24:8
  24. The prognosis of wild-type BRAF cutaneous melanoma (WT Bf-CM) patients remains poor due to the lack of therapeutic options. However, few studies have investigated the factors contributing to the prognosis of W...

    Authors: Ruizheng Sun, Yaozhong Liu, Cheng Lei, Zhenwei Tang and Lixia Lu
    Citation: Biological Procedures Online 2022 24:7
  25. Metastatic Axillary Lymph Node (mALN) status is currently the most important prognostic factor in the management of primary breast cancer (BC). Thus, development of specimens which enable identification of new...

    Authors: Vesna Ivanović, Nasta Dedović-Tanić, Zorka Milovanović, Bratislav Stojiljković, Miroslav Demajo and Vesna Mandušić
    Citation: Biological Procedures Online 2022 24:6
  26. Numerous cancer-associated deaths are owing to a lack of effective diagnostic and therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a precise, quick, and user-friendly te...

    Authors: Nasrin Bargahi, Samaneh Ghasemali, Samaneh Jahandar-Lashaki and Atefeh Nazari
    Citation: Biological Procedures Online 2022 24:5
  27. Objective Esophageal carcinoma (ESCA) is deadly cancer worldwide with unknown etiology. This study aimed to investigate the impact and mechanism of RAD6 on the development of Esophageal squamous cell carcinoma...

    Authors: Yu Deng, Yujiang Li, Tiantong Wu, Xuyuan Chen, Xiang Li, Kaican Cai and Xu Wu
    Citation: Biological Procedures Online 2022 24:4
  28. Flower color is one of the main characteristics of ornamental plants. Aurones are light yellow flavonoids produced in the petals of a limited number of plant species including snapdragon (Antirrhinum majus). As a...

    Authors: Amir Rajabi, Leila Fahmideh, Mojtaba Keykhasaber and Valiollah Ghasemi Omran
    Citation: Biological Procedures Online 2022 24:3
  29. Highly infectious illnesses caused by pathogens constitute severe threats to public health and lead to global economic loss. The use of robust and programmable clustered regularly interspaced short palindromic...

    Authors: Xiaolong Liu, Mubashir Hussain, Jianguo Dai, Yonghong Li, Lijun Zhang, Jian Yang, Zeeshan Ali, Nongyue He and Yongjun Tang
    Citation: Biological Procedures Online 2022 24:2
  30. Due to the importance of using cost-effective methods for therapeutic purposes, the function of probiotics as safe microorganisms and the study of their relevant functional mechanisms have recently been in the...

    Authors: Nahid Javanshir, Golsa Nayeb Ghanbar Hosseini, Mahdieh Sadeghi, Ramtin Esmaeili, Fateme Satarikia, Gholamreza Ahmadian and Najaf Allahyari
    Citation: Biological Procedures Online 2021 23:23
  31. Heregulin is a ligand for the protooncogene product ErbB/HER that acts as  a key mitogenic factor for human Schwann cells (hSCs). Heregulin is required for sustained hSC growth in vitro but must be thoroughly ...

    Authors: Paula V. Monje, Ketty Bacallao, Gabriela I. Aparicio and Anil Lalwani
    Citation: Biological Procedures Online 2021 23:22
  32. Because of the high frequency of chronic edema formation in the current “aged” society, analyses and detailed observation of post-surgical edema are getting more required. Post-surgical examination of the dyna...

    Authors: Shinji Kumegawa, Gen Yamada, Daiki Hashimoto, Tsuyoshi Hirashima, Mizuki Kajimoto, Kyoichi Isono, Kota Fujimoto, Kentaro Suzuki, Kazuhisa Uemura, Masatsugu Ema and Shinichi Asamura
    Citation: Biological Procedures Online 2021 23:21
  33. Auto-immune diseases involved at least 25% of the population in wealthy countries. Several factors including genetic, epigenetic, and environmental elements are implicated in development of Rheumatoid Arthriti...

    Authors: Zahra Payandeh, Abbas Pirpour Tazehkand, Ali Azargoonjahromi, Faezeh Almasi and Armina Alagheband Bahrami
    Citation: Biological Procedures Online 2021 23:20
  34. The detection of SARS-CoV-2 using qRT-PCR with the pooling of samples can reduce workload and costs especially when the prevalence rate of COVID-19 in a population is low.

    Authors: Imene Handous, Naila Hannachi, Manel Marzouk, Olfa Hazgui, Nissaf Bouafif Ep Ben Alaya and Jalel Boukadida
    Citation: Biological Procedures Online 2021 23:19
  35. In the area of oral and maxillofacial surgery, regenerative endodontics aims to present alternative options to conventional treatment strategies. With continuous advances in regenerative medicine, the source o...

    Authors: Benson Koh, Nadiah Sulaiman, Sharifah Nursyazwani Shahirah Wan Ismadi, Roszalina Ramli, Siti Salmiah Mohd Yunus, Ruszymah Bt Hj Idrus, Shahrul Hisham Zainal Ariffin, Rohaya Megat Abdul Wahab and Muhammad Dain Yazid
    Citation: Biological Procedures Online 2021 23:18
  36. The Interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein with Angiotensin converting enzyme 2 (ACE2) on the host cells is a crucial step for the viral entry and infect...

    Authors: Yuning Shang, Feixiang Chen, Shasha Li, Lijuan Song, Yunzhen Gao, Xinhua Yu and Junfeng Zheng
    Citation: Biological Procedures Online 2021 23:16
  37. Colorectal cancer (CRC) is a universal heterogeneous disease that is characterized by genetic and epigenetic alterations. Immunotherapy using monoclonal antibodies (mAb) and cancer vaccines are substitute stra...

    Authors: Ali Azadi, Alireza Golchini, Sina Delazar, Fatemeh Abarghooi Kahaki, Seyed Mohsen Dehnavi, Zahra Payandeh and Shirin Eyvazi
    Citation: Biological Procedures Online 2021 23:13
  38. Expression of stemness factors, such as octamer-binding transcription factor 3/4 (OCT3/4), sex determining region Y-box 2 (SOX2), and alkaline phosphatase (ALP) in human deciduous tooth-derived dental pulp cells ...

    Authors: Emi Inada, Issei Saitoh, Naoko Kubota, Yoko Iwase, Yuki Kiyokawa, Hirofumi Noguchi, Youichi Yamasaki and Masahiro Sato
    Citation: Biological Procedures Online 2021 23:12
  39. Although retinitis pigmentosa (RP) is most frequently studied in mouse models, rats, rabbits, and pigs are also used as animal models of RP. However, no studies have reported postnatal photoreceptor cell loss ...

    Authors: Chisato Inoue, Tamaki Takeuchi, Akira Shiota, Mineo Kondo and Yuji Nshizawa
    Citation: Biological Procedures Online 2021 23:11
  40. We investigated nasopharyngeal microbial community structure in COVID-19-positive and -negative patients. High-throughput 16S ribosomal RNA gene amplicon sequencing revealed significant microbial community str...

    Authors: Phillip A. Engen, Ankur Naqib, Cheryl Jennings, Stefan J. Green, Alan Landay, Ali Keshavarzian and Robin M. Voigt
    Citation: Biological Procedures Online 2021 23:10
  41. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Wonyoung Kang, Leigh Maher, Michael Michaud, Seong-Woo Bae, Seongyeong Kim, Hye Seung Lee, Seock-Ah Im, Han-Kwang Yang and Charles Lee
    Citation: Biological Procedures Online 2021 23:9

    The original article was published in Biological Procedures Online 2021 23:1

  42. Insufficient insulin secretion is a key component of both type 1 and type 2 diabetes. Since insulin is released by the islets of Langerhans, obtaining viable and functional islets is critical for research and ...

    Authors: Kathryn L. Corbin, Hannah L. West, Samantha Brodsky, Nicholas B. Whitticar, William J. Koch and Craig S. Nunemaker
    Citation: Biological Procedures Online 2021 23:7
  43. The proteostasis network includes all the factors that control the function of proteins in their native state and minimize their non-functional or harmful reactions. The molecular chaperones, the important med...

    Authors: Fateme Khomari, Mohsen Nabi-Afjadi, Sahar Yarahmadi, Hanie Eskandari and Elham Bahreini
    Citation: Biological Procedures Online 2021 23:8

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  • Citation Impact 2023
    Journal Impact Factor: 3.7
    5-year Journal Impact Factor: 4.6
    Source Normalized Impact per Paper (SNIP): 0.960
    SCImago Journal Rank (SJR): 1.048

    Speed 2023
    Submission to first editorial decision (median days): 8
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