Skip to main content

Table 1 Clinical features of patients (n = 45)

From: Macrophage-Derived MMP-9 and MMP-2 are Closely Related to the Rupture of the Fibrous Capsule of Hepatocellular Carcinoma Leading to Tumor Invasion

Variables

Repured FC (n = 26)

Intact FC(n = 19)

P value

Age(years), mean ± SD

57.92 ± 12.73

57.32 ± 10.09

0.863

Gender,n(%)

    

1.000

 Male

24

92.31%

17

89.47%

 

 Female

2

7.69%

2

10.53%

 

Hepatitis virus status, n (%)

    

0.029

 HBsAg ( +)

25

96.15%

14

73.68%

 

 HBsAg (-)

1

3.85%

5

26.32%

 

ALT (IU/L), n (%)

    

0.138

  > 40

12

46.15

13

68.42%

 

  ≤ 40

14

53.85%

6

31.58%

 

AST (IU/L), n (%)

    

0.463

  > 35

15

57.69%

13

68.42%

 

  ≤ 35

11

42.31%

6

31.58%

 

CEA(ng/ml)

    

0.365

  > 5

4

15.38%

5

26.32%

 

  ≤ 5

22

84.62%

14

73.68%

 

CA19-9(U/ml)

    

0.467

  > 27

8

30.77%

4

21.05%

 

  ≤ 27

18

69.23%

15

78.95%

 

CA125(U/ml)

    

0.103

  > 35

6

23.08%

1

5.26%

 

  ≤ 35

20

76.9%

18

94.74%

 

AFP(ng/ml)

    

0.033

  > 400

12

46.15%

3

15.79%

 

  ≤ 400

14

53.85%

16

84.21%

 

Vascular invasion, n (%)

    

0.006

 No

15

57.69%

18

94.74%

 

 Yes

11

42.31%

1

5.26%

 

Differentiation,n (%)

    

0.063

 Well or moderately

17

65.38%

17

89.47%

 

 Poorly

9

34.62%

2

10.53%

 

TNM Stage,n (%)

    

0.021

 I

15

57.69%

18

94.74%

 

 II

10

38.46%

1

5.26%

 

 III, IV

1

3.85%

0

0%

 

Recurrence

    

0.036

 Yes

19

73.08%

8

42.11%

 

 No

7

26.92%

11

57.89%

 
  1. SD Stand deviation,;HBsAg( +), hepatitis B surface antigen ( +) means HBV infection, conversely, HBsAg(-) indicates uninfected by HBV, ALT Alanine aminotransferase, AST Aspartate aminotransferase, CEA Carcinoembryonic antigen, CA19-9 Carbohydrate antigen 19–9, CA125 Carbohydrate antigen 125, AFP Alpha-fetoprotein levels, TNM Stage: T Tumor, N Nodes, M Metastasis, χ2 test
  2. P < 0.05