Fig. 3
Depletion results for alternative blocking oligonucleotide modifications. A Correlation plot between the log2 fold changes of noLNA and LNA1x samples between PRAD and CRC samples. Each dot is a miRNA and is colored by its p-value in the treated and untreated samples. B Significant gene concordance (i.e., the number of overlapping DE miRNAs between subsamples, as a measure for robustness) for four subsamples per sample type (no LNA and LNA1x) for different subsample sizes. C Read percentages for the YRNA and miRNA biotype for multiple modifications. D The number of discovered miRNAs and their coverage for the various modifications