Fig. 1

Knockdown of circ_0003570 promotes proliferation, migration and invasion of HCC cells in vitro. A qRT-PCR analysis of circ_0003570 expression in HCC cell lines and the immortalized human hepatic cell line LO2, *P < 0.05; **P < 0.01. B qRT-PCR analysis of circ_0003570 expression following transfected HCC cells with the siRNA of circ_0003570, *P < 0.05. C MTT assays and D colony formation assays showing that downregulation of circ_0003570 promoted the proliferation of HCC cells, *P < 0.05. E, F Transwell assays showed circ_0003570 knockdown reduced the migration and invasion of HCC cells. *P < 0.05. G, H Representative images of wound healing assays after circ_0003570 silencing. Student’s t-test was performed to compare the difference between two groups. *P < 0.05