Fig. 5

KDELR2 promotes BCa cell proliferation and metastasis in a KIF20A-mediated manner. A-B Detection of KIF20A, MMP2, MMP9 protein expressions by western blot analysis in the siKIF20A-1, siKIF20A-3 or KIF20A-overexpressing group (n = 3). C Knockdown of KIF20A could reverse the effect of KDELR2 overexpression on MMPs (n = 3). D CCK8 assays for the indicated cells (n = 4). E Migration and invasion assays (200x) for the indicated ccRCC cells (n = 3). p < 0.05, *; p < 0.01, **; p < 0.001, ***; p < 0.0001, ****