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Table 1 Clinico-pathological characteristics of WT Bf-CM patients

From: A novel 7 RNA-based signature for prediction of prognosis and therapeutic responses of wild-type BRAF cutaneous melanoma

Groups

Total (N = 211)

Training Group (N = 106)

Test Group (N = 105)

Gender

 Male

135(64.0%)

73(68.9%)

62(59.0%)

 Female

76(36.0%)

33(31.1%)

43(41.0%

Age At Diagnosis

 Median

62

63.5

61

 Range

25 ~ 87

30 ~ 87

25 ~ 83

 ≤ 58

90(42.7%)

42(39.6%)

48(45.7%)

 > 58

121(57.3%)

64(60.3%)

57(54.3%)

Tumor Tissue Site

 Primary Tumor

38(18.0%)

20(18.9%)

18(17.10%)

 Regional Cutaneous Or Subcutaneous Tissue

38(18.0%)

21(19.8%)

17(16.20%)

 Regional Lymph Node Metastasis

93(44.1%)

46(43.4%)

47(44.80%)

 Distant Metastasis

40(19.0%)

18(17.0%)

22(21.00%)

 Unknown

2(0.9%)

1(0.9%)

1(1.00%)

Pathological Stage

 0

4(1.9%)

1(0.9%)

3(2.90%)

 I

35(16.6%)

13(12.3%)

22(21.00%)

 II

63(29.9%)

33(31.1%)

30(28.60%)

 III

83(39.3%)

43(40.6%)

40(38.10%)

 IV

8(3.8%)

4(3.8%)

4(3.80%)

 Unknown

18(8.5%)

12(11.3%)

6(5.70%)

Anatomic Site

 Head And Neck

16(7.6%)

8(7.5%)

8(7.60%)

 Extremities

108(51.2%)

55(51.9%)

53(50.50%)

 Trunk

56(26.5%)

28(26.4%)

28(26.70%)

 Others/Unknown

31(14.7%)

15(14.2%)

16(15.20%)

Breslow Thickness (mm)

  < 2

54(25.5%)

26(24.6%)

28(26.70%)

 2 ~ 5

60(28.5%)

36(33.9%)

24(22.80%)

  > 5

53(25.1%)

25(23.6%)

28(26.70%)

 Unknown

44(20.9%)

19(17.9%)

25(23.80%)

Radiation Therapy

 Yes

37(17.5%)

20(18.9%)

17(16.20%)

 No

155(73.5%)

75(70.8%)

80(76.20%)

 Unknown

19(9.00%)

11(10.40%)

8(7.60%)

Vital Status

 Yes

81(38.4%)

36(34.0%)

45(42.90%)

 No

130(61.6%)

70(66.0%)

60(57.10%)