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Table 2 Relationship between expression of OTUB2, YAP1, TAZ and CTGF in ESCC and clinicopathological parameters

From: OTUB2 Regulates YAP1/TAZ to Promotes the Progression of Esophageal Squamous Cell Carcinoma

Clinicopathological parameters

N

OTUB2 expression

P

YAP1 expression

P

TAZ expression

P

CTGF expression

P

183

negative

positive

negative

positive

negative

positive

negative

positive

Gender

 Female

54

11

43

0.097

15

39

0.444

11

43

0.519

20

34

0.827

 Male

129

42

87

29

100

32

97

50

79

Age

  < 60

67

22

45

0.380

18

49

0.497

13

54

0.321

24

43

0.607

  ≥ 60

116

31

85

26

90

30

86

46

70

Tumor size

 <3

70

29

41

0.003

24

46

0.011

27

43

< 0.001

33

37

0.001

  ≥ 3

113

24

89

20

93

16

97

33

80

Degree of differentiation

 Well differentiated

67

27

40

0.037

22

45

0.037

19

48

0.128

27

40

0.712

 Moderately differentiated

98

22

76

21

77

23

75

35

63

 Poorly differentiated

18

4

14

1

17

1

17

8

10

Depth of invasion

 Mucosa

15

2

13

0.250

6

9

0.134

7

8

0.020

6

9

0.910

 Muscularis

90

30

60

24

66

24

66

33

57

 Full-thickness

78

21

57

14

64

12

66

31

47

pTNM stage

 IB

49

17

32

0.576

18

31

0.027

22

27

< 0.001

25

24

0.087

 IIA,B

113

30

83

24

89

20

93

39

74

 IIIA,B,C

21

6

15

2

19

1

20

6

15

Lymph node metastasis

 No

131

43

88

0.067

40

91

0.001

39

92

0.001

58

73

0.008

 Yes

52

10

42

4

48

4

48

12

40

  1. P<0.05, the difference was statistically significant