Fig. 4

Suppression of RAD6A expression inhibits ESCC growth in vivo. TE8 cells with or without depletion of RAD6A were injected into nude mice. A Volumes of xenograft tumors were measured and plotted; B weights of xenograft tumors; C Representative HE staining in tumor; D Representative immunohistochemical detection of RAD6A in tumor. ** P < 0.01, *** P < 0.001, **** P < 0.0001, vs sh-NC