Fig. 3

Knockdown RAD6A and RAD6B inhibit cell proliferation, migration and invasion of TE8 cells in vitro. TE8 cells were infected with lentiviruses expressing shRNA targeting RAD6A or RAD6B or shRNA control. A Western blot analysis of RAD6; B CCK-8 assays was used to assess the effect of cell proliferation after knocking down RAD6A and RAD6B; C and D Transwell assays were used to evaluate the effect of cell migration and invasion after knocking down RAD6A and RAD6B. * P < 0.05, *** P < 0.001, **** P < 0.0001, vs sh-NC