Fig. 4
From: AVL9 promotes colorectal carcinoma cell migration via regulating EGFR expression
AVL9 upregulated EGFR protein level expression. A Western blot analysis confirmed the effect of AVL9 on tumor-related factors in RKO-Lv3-shAVL9/ RKO-Lv3-shNC and HCT116-Lv6-AVL9/HCT116-Lv6-NC cells. Silencing AVL9 reduced the expression of EGFR at protein level in RKO-Lv3-shAVL9 cell compared to RKO-Lv3-shNC, simultaneously, AVL9 overexpression upregulated the protein level of EGFR expression in HCT116-Lv6-AVL9 compared to the control group (B). The bar graph showed the relative intensity of tumor-related protein normalized by β-actin *P<0.05