Fig. 4From: A Practical Guide to Rodent Islet Isolation and Assessment RevisitedExamples of both under digested and over digested islets immediately post isolation and purification. a Under digested islets will typically contain large amounts of acinar tissue appearing dark brown or black. Islets are often aggregated near the masses of acinar tissue as shown. Separating islets from these under digested clumps is often difficult. b Over digested islet preparations result in large amounts of pancreatic debris consisting of tiny fragments of acinar tissue and digested isletsBack to article page