Table 2 Summary of the mentioned virus detection methods
From: Potential Diagnostic Systems for Coronavirus Detection: a Critical Review
Method | Advantages | limitations |
|---|---|---|
IF methods | Inexpensive, accessibility, ease of operation, easy interpretation of results | Antisera concentration, the inability of the detection of new strains/species, instability of antibodies |
NAATs | Ease of purification and separation of nucleic acids from antibodies, Excellent sensitivity, and specificity | Expensive, the technical expertise required |
Electron microscopy | Accessible | The inability of the specific diagnosis of viruses |
Cell culture | Capacity to isolate a wide variety of viruses, ease of operation | The long incubation period for some viruses, |
Aptamer- based | Easy synthesize and modification of aptamers, a broad range of targets, inexpensive | Some methods need expert operators |