Fig. 6
From: Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy
Histological comparison of spheroids and human tissue. a Normal LF tissue with abundant normal elastin fibers organized in parallel. b LFH tissue with disorganized and fragmented elastic fibers. c 2D LF cells were randomly distributed on the slides. d Frozen sections of 3D spheroids. Many nuclei could be observed and exhibited compact, nondirectional aggregation. Scale bars = 200 μm