Fig. 5
From: Efficient In Vivo Introduction of Point Mutations Using ssODN and a Co-CRISPR Approach
Phenotypic examination of the generated flies. Nup107D364N mutant flies exhibited a ovarian dysgenesis and b reduced progeny, as compared to WT control flies. ctinmDPE transgenic flies show reduced endogenous tin RNA levels at 2-4 h after eggs laying, as measured by RT-PCR. The location of the amplicons is depicted relative to the tin gene. Student’s T-test was used to calculate statistical significance of the result, ***p < 0.0002 **p < 0.01