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Table 1 GPCRs tested in this study. Receptors are given in order from high to low expression [33]

From: Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets

GPCRAgonistCoupling propertiesIslet expression profile
GLP-1RGLP-1Gsβ cell > > α cell > δ cell
SstR1–5somatostatinGiubiquitous
P2Y6UDPGq/11β cell > δ cell > > α cell
M3RacetylcholineGq/11β cell > δ cell > α cell
FFAR2acetateGi / Gq/11ubiquitous
V1RAVPGq/11δ cell = α cell
GHS-RghrelinGq/11δ cell > > > α cell > β cell