Fig. 5
From: Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets
Ca2+ imaging of pancreatic islets. a Ca2+ imaging experiments were performed in single pancreatic islets loaded with fura-2 AM. Images show the fluorescence ratio (F340/F380) of one islet before and after addition of 300 nM ghrelin and 100 μM CCh. b Time course of Ca2+ responses in three regions within the islet is shown and corresponds to (a). c Images show the fluorescence ratio (F340/F380) of another islet before and after addition of 100 nM AVP and 100 μM CCh. d Time course of Ca2+ responses in three regions within the islet is shown and corresponds to (c)