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Table 4 Validation of developed immunostick test for screening of α-thalassemia 1 SEA type deletion carriers

From: Immunostick Test for Detecting ζ-Globin Chains and Screening of the Southeast Asian α-Thalassemia 1 Deletion

Immunostick test for ζ-globin chain

PCR analysis for SEA 훼-thalassemia 1

Total

Positive

Negative

Positive

53

17

70

Negative

0

78

78

Total

53

95

148

  1. Sensitivity (53/53) × 100 = 100%
  2. Specificity (78/95) × 100 = 82%
  3. Positive predictive value (53/70) × 100 = 76%
  4. Negative predictive value (78/78) × 100 = 100%