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Table 1 Enriched gene ontology terms in the CCAT1 wild-type versus CCAT1 knockout transcriptomes derived from differentially expressed genes (in the category of molecular function)

From: CRISPR/Cas9 Knockout Strategies to Ablate CCAT1 lncRNA Gene in Cancer Cells

ID

Term

Gene Count

p Valuea

GO:0004867

serine-type endopeptidase inhibitor activity

9

2.50E-04

GO:0016491

oxidoreductase activity

12

6.60E-04

GO:0005515

protein binding

171

9.60E-03

GO:0008236

serine-type peptidase activity

5

2.30E-02

GO:0004879

RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding

4

2.30E-02

GO:0004252

serine-type endopeptidase activity

10

3.10E-02

GO:0015485

cholesterol binding

4

3.30E-02

GO:0004029

aldehyde dehydrogenase (NAD) activity

3

3.30E-02

GO:0032810

sterol response element binding

2

3.40E-02

GO:0003727

single-stranded RNA binding

4

3.70E-02

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

3

4.10E-02

GO:0004715

non-membrane spanning protein tyrosine kinase activity

4

4.40E-02

GO:0005506

iron ion binding

7

4.70E-02

GO:0003779

actin binding

10

4.90E-02

  1. aOnly GO terms with p value of less than 0.05 are shown