Skip to main content
Fig. 2 | Biological Procedures Online

Fig. 2

From: Blockade of ITGA2 Induces Apoptosis and Inhibits Cell Migration in Gastric Cancer

Fig. 2

The anti-ITGA2 antibody induced apoptosis in AGS cells but not SUN-1 cells. a Human gastric cancer cell lines AGS and SUN-1 were treated with different concentrations of an anti-ITGA2 antibody for 48 h, and cell survivals were measured by an MTT assay. An isotype control antibody was used as a negative control. b AGS cells were treated with mitomycin C as a positive control, or incubated with 0.3 μg of anti-ITGA2 antibodies or isotype control (negative control) for 48 h. Cells were stained with PE-conjugated anti-active caspase-3 antibodies, and analyzed by flow cytometry. The percentages of caspase-3 positive-staining cells summarized in the right panel, showing mean ± standard deviation (S.D). Statistical comparisons were made by one-way ANOVA or two-way ANOVA with Bonferroni comparisons. * p < 0.05 and **** p < 0.0001. Data are representative of three independent experiments

Back to article page