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Table 2 Mechanism of Action of Herbal Mixtures

From: Cancer chemoprevention and therapy using chinese herbal medicine

Name

Botanical Origin

Biological/Pharmacological Activity

Potential Active Components

Latin

Chinese Pinyin

Single Herbs

Green tea

Lv Cha

Nonfermented leaves of the plant Camellia sinensis

Apoptosis, cell cycle arrest,

growth inhibition, antiangiogenesis, and inhibition of metastasis [87]

Epicatechin,

Epigallocatechin,

Epicatechin-3-gallate,Epigallocatechin-3-gallate [87],

Panax ginseng C. A. Mey.

Ren Shen

Fleshy roots

Apoptosis [125], cell cycle arrest,

growth inhibition, antiangiogenesis,

anti-tumor [125, 126]

EFLA400 [21]

Prunella vulgaris L.

Xia Ku Cao

Dried spikes of the Labiatae plant PV.

Immune modulatory [52, 127],

antiestrogenic [128],

antiestrogen receptor [51],

anti-tumor [127]

Rosmarinic, ellagic and caffeic acids [129],Phenolic acids, flavonoids,

coumarins, triterpense,

volatile oil, polysaccharides [50, 127]

Scutellaria barbata D. Don

Ban Zhi Lian

Aqueous extract from Scutellaria barbata

Anti-inflammatory and anti-tumor [22]

BZL101 [22, 130]

Magnolia officinalis

Hou Pu

Root and stem bark of the oriental herb Magnolia officinalis

Anti-inflammatory [131], anti–gastric ulcer, anti-allergic, antibacterial, and antithrombotic properties [110],

Honokiol and magnolol [132, 133],rosmarinic acid

Curcuma longa L.

Jiang Huang

Root of the Curcuma Longa

Anti-inflammatory, antioxidant [134, 135]

Curcumin [23]α-pinene, β-pinene, γ-terpinene,

p-cymene, cuminaldehyde, carvone, 1,8-cineole, β-carotene, β-sitosterol, caffeic acid,carvacrol, carvaol, geranial, kaempferol, limonene, p-coumaric acid, quercetin, tannin, thymol [135]

Formula

Anti-tumor B (ATB), also known as Zeng Sheng Ping(增生平)

Zeng Sheng Ping Pian

Mixture composed of six plants:

Sophoratonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus brachyotus, Dictamnus dasycarpus, and Dioscorea bulbifera.

Anti-tumor [29]

NA

BaoFei Decoction

Bao Fei Yin

Clerodendrum bungei,

Solanum nigrum L.,

Platycodon grandiflorus,

Glycyrrhiza uralensis Fisch,

Anti-tumor [136, 137]

NA

Liu-Wei-Di-Huang Wan

Liu Wei Di Huang Wan

Mixture composed of Six plants:

Formula contains Rehmannia glutinosa, Cornus officinalis Sieb., Common Yam Rhizome, Alisma orientalis, Tree Peony Bark, and Poria cocos

Immune modulatory,

anti-tumor [34, 35]

NA

  1. NA: not applicable