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Table 2 Mechanism of Action of Herbal Mixtures

From: Cancer chemoprevention and therapy using chinese herbal medicine

Name Botanical Origin Biological/Pharmacological Activity Potential Active Components
Latin Chinese Pinyin
Single Herbs
Green tea Lv Cha Nonfermented leaves of the plant Camellia sinensis Apoptosis, cell cycle arrest,
growth inhibition, antiangiogenesis, and inhibition of metastasis [87]
Epicatechin,
Epigallocatechin,
Epicatechin-3-gallate,Epigallocatechin-3-gallate [87],
Panax ginseng C. A. Mey. Ren Shen Fleshy roots Apoptosis [125], cell cycle arrest,
growth inhibition, antiangiogenesis,
anti-tumor [125, 126]
EFLA400 [21]
Prunella vulgaris L. Xia Ku Cao Dried spikes of the Labiatae plant PV. Immune modulatory [52, 127],
antiestrogenic [128],
antiestrogen receptor [51],
anti-tumor [127]
Rosmarinic, ellagic and caffeic acids [129],Phenolic acids, flavonoids,
coumarins, triterpense,
volatile oil, polysaccharides [50, 127]
Scutellaria barbata D. Don Ban Zhi Lian Aqueous extract from Scutellaria barbata Anti-inflammatory and anti-tumor [22] BZL101 [22, 130]
Magnolia officinalis Hou Pu Root and stem bark of the oriental herb Magnolia officinalis Anti-inflammatory [131], anti–gastric ulcer, anti-allergic, antibacterial, and antithrombotic properties [110], Honokiol and magnolol [132, 133],rosmarinic acid
Curcuma longa L. Jiang Huang Root of the Curcuma Longa Anti-inflammatory, antioxidant [134, 135] Curcumin [23]α-pinene, β-pinene, γ-terpinene,
p-cymene, cuminaldehyde, carvone, 1,8-cineole, β-carotene, β-sitosterol, caffeic acid,carvacrol, carvaol, geranial, kaempferol, limonene, p-coumaric acid, quercetin, tannin, thymol [135]
Formula
Anti-tumor B (ATB), also known as Zeng Sheng Ping(增生平) Zeng Sheng Ping Pian Mixture composed of six plants:
Sophoratonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus brachyotus, Dictamnus dasycarpus, and Dioscorea bulbifera.
Anti-tumor [29] NA
BaoFei Decoction Bao Fei Yin Clerodendrum bungei,
Solanum nigrum L.,
Platycodon grandiflorus,
Glycyrrhiza uralensis Fisch,
Anti-tumor [136, 137] NA
Liu-Wei-Di-Huang Wan Liu Wei Di Huang Wan Mixture composed of Six plants:
Formula contains Rehmannia glutinosa, Cornus officinalis Sieb., Common Yam Rhizome, Alisma orientalis, Tree Peony Bark, and Poria cocos
Immune modulatory,
anti-tumor [34, 35]
NA
  1. NA: not applicable