Figure 1
From: Next generation sequencing in cancer research and clinical application
The workflow of integrating omics data in cancer research and clinical application. NGS technologies detect the genomic, transcriptomic and epigenomic alternations including mutations, copy number variations, structural variants, differentially expressed genes, fusion transcripts, DNA methylation change, etc. Various kinds of bioinformatics tools are used to analyze, integrate, and interpret the data to improve our understanding of cancer biology and develop personalized treatment strategy.