Flanking nucleotide sequences of the CEA and SARS epitopes. (a) 132 bps (nucleotides 12804~10935) of the CEA sequence (NCBI accession No. Z21818) and (b) 177 bps of the SARS sequence (NCBI accession No. AB263618) were used as the starting materials to generate highly-immunogenic mutations. The grey area indicates the epitope used for affinity prediction.