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Table 3 Morphometric measurements of ACF with crypts ≥5 that differentiate non-MDF and MDF

From: A Method for Serial Tissue Processing and Parallel Analysis of Aberrant Crypt Morphology, Mucin Depletion, and Beta-Catenin Staining in an Experimental Model of Colon Carcinogenesis

ACF Area (μm2) IOD Diameter (μm) Perimeter (μm)
Non-MDF (n = 819) 32,207 ± 522 15,134 ± 336 195 ± 2 650 ± 5
MDF (n = 28) 25,820 ± 1429 10,995 ± 839 176 ± 5 593 ± 16
p 0.02 0.02 0.03 0.04
  1. Values are means ± SEM based on number of crypts ≥5 per ACF
  2. Statistically significant differences were observed, p ≤ 0.05