Fig. 9

NDI1 can compensate for the impaired mitochondrial oxidative phosphorylation in SN of MPTP-induced PD mouse model. A: The mitochondrial total oxygen consumption of complex I and complex II (CI+CII), the oligomycin-treated and FCCP-treated oxygen consumption. B: RCR (respiratory control rate) was calculated by (CI+ CII)/Oligo. C: LCR (leakage control ratio) was calculated by Oligo/FCCP. D: The mitochondrial complex I enzyme activity in SN was detected by measuring NADH oxidation rate. ns: no significant difference, *: P < 0.05, **: P < 0.01, ***: P < 0.001