Fig. 8

NDI1 can inhibit inflammatory response (decrease the number of astrocytes and microglia) and maintain number of neurons in SN of MPTP-induced PD mouse model. A, B, C: Astrocytes (GFAP-positive, cytoplasm), microglia (Iba-1-positive, cytoplasm), neurons (NeuN-positive, nucleus) were detected by immunohistochemical staining with GFAP antibody, Iba-1 antibody and NeuN antibody, respectively. (Scale bar: 100 μm). D, E, F: Statistical analysis of the proportion of astrocytes (GFAP-positive), microglia (Iba-1 positive), neurons (NeuN-positive). ns: no significant difference, *: P < 0.05, **: P < 0.01, ***: P < 0.001