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Fig. 2 | Biological Procedures Online

Fig. 2

From: Targeting Mitochondrial Complex I Deficiency in MPP+/MPTP-induced Parkinson’s Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene

Fig. 2

NDI1 can partially restore the oxidative phosphorylation function of mitochondria in MPP+-induced PD cell culture model. A: The basal (Base), oligomycin-treated (Oligo), and FCCP-treated (FCCP) oxygen consumption. B: RCR (respiratory control rate) calculated by Base/Oligo. C: LCR (leakage control rate) calculated by Oligo/FCCP. D: Complex I-dependent oxygen consumption detected by cellular respiration apparatus. E: Statistical analysis of complex I-dependent oxygen consumption. F: The proportion of rotenone or flavone sensitive in complex I-dependent oxygen consumption. G: The basal ATP production (Base) and oligomycin-sensitive ATP production (Oligo-sensitive). H: The ratio of Oligo-sensitive ATP production. ns: not significant, *: P < 0.05, **: P < 0.01, ***: P < 0.001

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Biological Procedures Online

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