Fig. 4
MBD3 promoted GC cell proliferation. A, B MBD3 downregulation inhibited the proliferation of MGC-803 and HGC-27 cells. C, D MBD3 upregulation promoted the proliferation of SGC-7901 and MGC-803 cells. All experiments were performed using at least three biological replicates. E, F MBD3 downregulation weakened colony formation in MGC-803 and HGC-27 cells. G, H MBD3 upregulation enhanced colony formation in SGC-7901 and MGC-803 cells. I, J MGC-803 cells with MBD3 upregulation were injected (2 × 10.6 cells/site) subcutaneously into a mouse, and the tumor volume was measured weekly (n = 5 mice). (*P < 0.05)