Fig. 1

The expression of MBD3 in GC tissues and cells. A MBD3 expression in different cancer types based on the TCGA database. B The expression of MBD3 was higher in GC than in normal gastric tissues from the GTEx database (normal 174 patients) and (C) TCGA database (normal 36 patients, tumor 414 patients). D MBD3 expression in TCGA-paired GC and normal tissues (normal 27 patients, tumor 27 patients). E IHC staining for MBD3 in GC and matched paracancerous tissues from three representative patients. Original magnifications 20 × and 40 × (inset panels). F, G Western blotting and qRT-PCR were used to measure the relative expression levels of MBD3 in different gastric cell lines (GES-1, SGC-7901, HGC-27 and MGC-803). (*P < 0.05, **P < 0.01, ***P < 0.001)