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Table 1 Clinical Baseline Characteristics

From: Immune Activation Effects at Different Irradiated Sites and Optimal Timing of Radioimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer: a Real-World Analysis

All patients, n = 45

No. (%)

   

Sex

Male

Female

  

31 (68.9)

14 (31.1)

  

Age (years)

≤ 60

> 60

Median

 

26 (57.8)

19 (42.2)

59

 

ECOG performance status

≤ 1

≥ 2

  

32(71.1)

13 (28.9)

  

BMI

Median (range)

   

24.3 (17.3–31.8)

   

Smoking history

Never

Current or former

unknown

 

9 (20.0)

32 (71.1)

4 (8.9)

 

Treatment stage

First-line

Second-line

Third-line and more

 

12 (26.7)

28 (62.2)

5 (11.1)

 

Immunotherapy mode

ICI

ICI + CT

ICI + VEGFR

ICI + CT + VEGFR

10 (22.2)

24 (53.3)

8 (17.8)

3 (6.7)

Irradiated site

Brain

Bone

Lung (drainage area lymph node)

 

22 (48.9)

13 (28.9)

10 (22.2)

 

RT modality

CFRT

SBRT

  

44 (97.8)

1 (2.2)

  
  1. Abbreviations: No. Number, ECOG Eastern Cooperative Oncology Group, BMI Body Mass Index, ICI Immune Checkpoint Inhibitor, CT Chemotherapy, VEGFR Vascular Endothelial Growth Factor Receptor, RT Radiotherapy, CFRT Conventional Fractionated Radiotherapy, SBRT Stereotactic Body Radiotherapy