Fig. 4

Association of immune checkpoint proteins with efficacy of ICI plus chemotherapy. Comparisons of immune checkpoint proteins (ICPs) expressions on immune cell subsets in different subgroups: Indicators comparison between patients pre- and after-treatment (A). Pre-treat indicators comparison between patients in CB and NB groups (B). After-treat indicators comparison between patients in CB and NB groups (C). Dynamic changes of indicators comparison between patients in CB and NB groups (D). Abbreviations: CB, clinical benefits, NB, non-benefit. *P < 0.1, ** P < 0.05