Table 1 High-throughput screening of NCI library of 240 natural products (Natural products set IV 13160330 https://dtp.cancer.gov/organization/dscb/obtaining/available_plates.htm)
Summary of High-throughput screening | |
|---|---|
Total number of Natural products screened | 240 |
Initial Screening Concentration of 240 Natural products | 10 µM |
Primary Hits (> 80% inhibition of infection) | 24 |
Hit Rate (%) | 10 |
Positive hits after reconfirmation of primary Hits with dose response up to 1 µM | 6 |
Reconfirmation rate (%) | 16.6 |
EC50 < 1 µM | 6 |